Concepedia

Receptor Complex Assembly

Receptor Complex Assembly is a molecular mechanism in innate immune signaling wherein pattern recognition receptors oligomerize with downstream adapter proteins to form a functional signaling platform that initiates host defense responses upon pathogen detection.

740

Publications

69.7K

Citations

3.6K

Authors

851

Institutions

Publications per year

2017–2026

90

Parents

Publications

740

MyD88: An Adapter That Recruits IRAK to the IL-1 Receptor Complex

Holger Wesche, William J. Henzel, Wendy Shillinglaw et al. · Immunity · 1997 · 1.1K citations · Full text

, , +12

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

Su‐Chang Lin, Yu-Chih Lo, Hao Wu · Nature · 2010 · 1.1K citations

, , +14

A Hierarchical Network of Interreceptor Interactions Determines Signal Transduction by Neu Differentiation Factor/Neuregulin and Epidermal Growth Factor

Eldad Tzahar, Hadassa Waterman, Xiomei Chen et al. · Molecular and Cellular Biology · 1996 · 1K citations · Full text

, , +17

Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons

RJ Wenthold, RS Petralia, II Blahos J et al. · Journal of Neuroscience · 1996 · 843 citations · Full text

, , +13

Mutations in Two Genes Encoding Different Subunits of a Receptor Signaling Complex Result in an Identical Disease Phenotype

Juha Paloneva, Tuula Manninen, Grant P. Christman et al. · The American Journal of Human Genetics · 2002 · 700 citations · Full text

, , +8

1–5 of 740

Authors

3.6K

  1. KC
    K. Christopher García

    Stanford University, United States

    9 publications · 2K citations

    10

    h-index

  2. WB
    William B. Pratt

    University of Michigan, United States

    9 publications · 922 citations

    9

    h-index

  3. JP
    Jacob Piehler

    Osnabrück University, Germany

    8 publications · 1K citations

    9

    h-index

  4. SR
    Stefan Rose‐John

    Christian-Albrechts-Universität zu Kiel, Germany

    7 publications · 363 citations

    7

    h-index

  5. PC
    Peter C. Heinrich

    RWTH Aachen University, Germany

    7 publications · 438 citations

    7

    h-index

1–5 of 3.6K

Institutions

851

  1. National Institutes of Health

    Bethesda, United States

    26 h-index

    77 publications

    14.4K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    26 h-index

    90 publications

    12.7K citations

  3. Harvard University

    Cambridge, United States

    18 h-index

    54 publications

    4.2K citations

  4. Inserm

    Paris, France

    16 h-index

    71 publications

    7.5K citations

  5. Stanford University

    Stanford, United States

    15 h-index

    69 publications

    11.4K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    34 publications

    2.7K citations

  7. The University of Osaka

    Osaka, Japan

    13 h-index

    54 publications

    9.9K citations

  8. National Cancer Institute

    Bethesda, United States

    12 h-index

    46 publications

    4.5K citations

1–8 of 851

Venues

  1. Journal of Biological Chemistry

    JBC · 137 publications · 12.2K citations

    62

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 52 publications · 7K citations

    43

    h-index

  3. Science

    23 publications · 7.3K citations

    23

    h-index

  4. The Journal of Immunology

    JI · 27 publications · 2.7K citations

    22

    h-index

  5. PubMed

    Repository · 21 publications · 827 citations

    15

    h-index

1–5