Jacob Piehler

Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling

Claudia Y. Janda, Luke T. Dang, Changjiang You et al. · Nature · 2017 · 409 citations

Signal Transduction, Signaling Pathway, Medicine +5

High-Affinity Adaptors for Switchable Recognition of Histidine-Tagged Proteins

Suman Lata, Annett Reichel, Roland Brock et al. · Journal of the American Chemical Society · 2005 · 377 citations

Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons

Christoph Thomas, Ignacio Moraga, Doron Levin et al. · Cell · 2011 · 351 citations

Ligand Discrimination, Signal Transduction, Functional Selectivity +12

Helical Structures of ESCRT-III Are Disassembled by VPS4

Suman Lata, Guy Schoehn, Ankur Jain et al. · Science · 2008 · 342 citations · Full text

Crystal Structure, Intracellular Membrane Trafficking, Protein Secretion +18

USP18-Based Negative Feedback Control Is Induced by Type I and Type III Interferons and Specifically Inactivates Interferon α Response

Véronique François-Newton, Gabriel Magno de Freitas Almeida, Béatrice Payelle‐Brogard et al. · PLoS ONE · 2011 · 260 citations · Full text

Innate Immune System, Immunology, Immune Regulation +21