Nrf2 antioxidant defense is involved in survival signaling elicited by 27-hydroxycholesterol in human promonocytic cells

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 176.9K citations

Functional Genomics, Engineering, Medicine +12

An oxysterol signalling pathway mediated by the nuclear receptor LXRα

Bethany A. Janowski, Patricia J. Willy, Thota Rama Devi et al. · Nature · 1996 · 1.7K citations

Molecular Physiology, Signal Transduction, Signaling Pathway +8

Structural requirements of ligands for the oxysterol liver X receptors LXRα and LXRβ

Bethany A. Janowski, Michael J. Grogan, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 1999 · 926 citations

Molecular Biology, Chemical Biology, Redox Biology +16

27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiology

Erik R. Nelson, Suzanne E. Wardell, Jeff S. Jasper et al. · Science · 2013 · 819 citations · Full text

Tumor Biology, Breast Oncology, Oncology +11

Regulation of Heme Oxygenase-1 Expression through the Phosphatidylinositol 3-Kinase/Akt Pathway and the Nrf2 Transcription Factor in Response to the Antioxidant Phytochemical Carnosol

Daniel Martı́n, Ana I. Rojo, Marta Salinas et al. · Journal of Biological Chemistry · 2004 · 696 citations · Full text

Lipid Peroxidation, Nrf2 Transcription Factor, Cell Death +18