Changes in brain oxysterols at different stages of Alzheimer's disease: Their involvement in neuroinflammation

Gabriella Testa, Erica Staurenghi, Chiara Zerbinati, +7

Redox Biology

Relation between TLR4/NF‐κB signaling pathway activation by 27‐hydroxycholesterol and 4‐hydroxynonenal, and atherosclerotic plaque instability

Simona Gargiulo, Paola Gamba, Gabriella Testa, +4

Aging Cell

Vascular DiseaseInflammatory Lung DiseaseLipid PeroxidationImmunologyPathology +23

Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer’s disease: three partners in crime

Paola Gamba, Gabriella Leonarduzzi, Elena Tamagno, +8

Aging Cell

Loading into Nanoparticles Improves Quercetin's Efficacy in Preventing Neuroinflammation Induced by Oxysterols

Gabriella Testa, Paola Gamba, Simona Gargiulo, +7

PLoS ONE

Lipid PeroxidationCell DeathRedox BiologyOxidative StressFree Quercetin +21

Oxysterol-induced up-regulation of MCP-1 expression and synthesis in macrophage cells

Gabriella Leonarduzzi, Paola Gamba, Barbara Sottero, +8

Free Radical Biology and Medicine

MitophagySignal TransductionCell RegulationBiochemistryOxysterol +9

Early Involvement of ROS Overproduction in Apoptosis Induced by 7-Ketocholesterol

Gabriella Leonarduzzi, Barbara Vizio, Barbara Sottero, +6

Antioxidants and Redox Signaling

Lipid PeroxidationApoptosisImmunologyCell DeathHyperlipidemia +19

25-Hydroxycholesterol and 27-hydroxycholesterol inhibit human rotavirus infection by sequestering viral particles into late endosomes

Andrea Civra, Rachele Francese, Paola Gamba, +4

Redox Biology

Up‐regulation of β‐amyloidogenesis in neuron‐like human cells by both 24‐ and 27‐hydroxycholesterol: protective effect of <i>N</i>‐acetyl‐cysteine

Paola Gamba, Michela Guglielmotto, Gabriella Testa, +10

Aging Cell

Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2

Erica Staurenghi, Valentina Cerrato, Paola Gamba, +8

Redox Biology

Neurodegenerative DiseasesReactive AstrocytesAlzheimer's DiseaseOxysterolOxysterols Present +12

Plaque oxysterols induce unbalanced up-regulation of matrix metalloproteinase-9 in macrophagic cells through redox-sensitive signaling pathways: Implications regarding the vulnerability of atherosclerotic lesions

Simona Gargiulo, Barbara Sottero, Paola Gamba, +3

Free Radical Biology and Medicine

ImmunologyMacrophagic CellsRedox BiologyOxidative StressInflammation +15