Concepedia

A CRISPR-Cas9 gene drive system targeting female reproduction in the malaria mosquito vector Anopheles gambiae

Andrew Hammond, Roberto Galizi, Kyros Kyrou, Alekos Simoni, Carla Siniscalchi, Dimitris Katsanos, Matthew O. Gribble, Dean A. Baker, Éric Marois, Steven Russell,

Nature Biotechnology · 2015 · 1.3K citations · 29 references

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29

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

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DNA targeting specificity of RNA-guided Cas9 nucleases

Patrick D. Hsu, David A. Scott, Joshua A. Weinstein et al. · Nature Biotechnology · 2013 · 4.9K citations · Full text

, , +10

Efficient genome editing in zebrafish using a CRISPR-Cas system

Woong Y. Hwang, Yanfang Fu, Deepak Reyon et al. · Nature Biotechnology · 2013 · 3K citations · Full text

, , +13

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

Tomáš Čermák, Erin Doyle, Michelle Christian et al. · Nucleic Acids Research · 2011 · 2.1K citations · Full text

, , +10

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

Yanfang Fu, Jeffry D. Sander, Deepak Reyon et al. · Nature Biotechnology · 2014 · 2K citations · Full text

, , +14