Opposite Regulation of the Human Paraoxonase-1 Gene PON-1 by Fenofibrate and Statins

Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase.

Mira Rosenblat, C L Bisgaier, Roger S. Newton et al. · Journal of Clinical Investigation · 1998 · 1.2K citations · Full text

Life Sciences, Biochemistry, Lipid Biochemistry +16

Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis

Diana M. Shih, Lingjie Gu, Yu-Rong Xia et al. · Nature · 1998 · 1.1K citations

Pharmacy, Biochemistry, Toxicology +9

The Human Serum Paraoxonase/Arylesterase Gene (PON1) Is One Member of a Multigene Family

S.L. Primo-Parmo, Robert C. Sorenson, John F. Teiber et al. · Genomics · 1996 · 674 citations

Life Sciences, Genetics, Molecular Genetics +4

The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin

Holly Davies, Rebecca J. Richter, Matthew Keifer et al. · Nature Genetics · 1996 · 598 citations

Veterinary Medicine, Genetics, Pharmacology +5

Paraoxonase-2 Is a Ubiquitously Expressed Protein with Antioxidant Properties and Is Capable of Preventing Cell-mediated Oxidative Modification of Low Density Lipoprotein

Carey J. Ng, David J. Wadleigh, Aditya Gangopadhyay et al. · Journal of Biological Chemistry · 2001 · 462 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17