Evaluation of the Glidant Property of Fonio Starch

Abstract

Fonio starch was evaluated as a glidant in comparison with corn starch and talc in Folic acid tablet formulation. The glidant property was analysed using the Flow rate, flow factor and angle of Repose of the granules while the quali ty of the tabl et was assessed by crushi ng str ength, Friability, disintegration and dissolution times of the tablet. The result of angle of repose, flow rate and flow factor indicated that Fonio starch compares well with both corn starch and talc at concentration of 2%w/w and at that concentration the tablet properties (crushing strength, friability, disintegration and dissolution times) were similar, it may therefore serve as an alternative glidant for pharmaceutical granulations.