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High affinity ligands for the α7 nicotinic receptor that show no cross-reactivity with the 5-HT3 receptor

Stephen Baker, John R. Boot, Michael Brunavs, David Dobson, Rachel Green, Lorna Hayhurst, Martine Keenan, Louise Wallace

Bioorganic & Medicinal Chemistry Letters · 2005 · 17 citations · 8 references

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References

8

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

Katjuša Brejc, Willem J. van Dijk, Remco V. Klaassen et al. · Nature · 2001 · 1.8K citations

, , +17

A glia-derived acetylcholine-binding protein that modulates synaptic transmission

August B. Smit, Naweed I. Syed, Dick Schaap et al. · Nature · 2001 · 567 citations

, , +14

Neuronal Nicotinic Acetylcholine Receptors as Novel Drug Targets

G. Kenneth Lloyd, Michael Williams · Journal of Pharmacology and Experimental Therapeutics · 2000 · 312 citations

, , +17

Discovery and Structure−Activity Relationship of Quinuclidine Benzamides as Agonists of α7 Nicotinic Acetylcholine Receptors

Alice L. Bodnar, Luz Cortes-Burgos, Karen K. Cook et al. · Journal of Medicinal Chemistry · 2005 · 216 citations · Full text

, , +17

The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective α7 nicotinic receptor partial agonist

John E. Macor, David Gurley, Thomas H. Lanthorn et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 159 citations · Full text

, , +15