David Gurley

The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective α7 nicotinic receptor partial agonist

John E. Macor, David Gurley, Thomas H. Lanthorn et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 157 citations · Full text

Point mutations in the M2 region of the alpha, beta, or gamma subunit of the GABAA channel that abolish block by picrotoxin.

David Gurley, Phil C. Ross, David S. Weiss et al. · PubMed · 1995 · 141 citations

M2 Region, Molecular Biology, Molecular Genetics +19

(−)-Spiro[1-azabicyclo[2.2.2]octane-3,5‘-oxazolidin-2‘-one], a Conformationally Restricted Analogue of Acetylcholine, Is a Highly Selective Full Agonist at the α7 Nicotinic Acetylcholine Receptor

G. B. MULLEN, James Napier, Michael Balestra et al. · Journal of Medicinal Chemistry · 2000 · 132 citations · Full text

Pharmacotherapy, Social Sciences, Molecular Pharmacology +19

Distinct Pharmacologic Properties of Neuromuscular Blocking Agents on Human Neuronal Nicotinic Acetylcholine Receptors

Malin Jonsson Fagerlund, David Gurley, Michael Dabrowski et al. · Anesthesiology · 2006 · 101 citations · Full text

Selective α7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes

S G Sydserff, Evelynjeane J. Sutton, Dekun Song et al. · Biochemical Pharmacology · 2009 · 96 citations

Cognitive Science, Brain Function, Synaptic Signaling +11