David Gurley - Concepedia

Concepedia

Author

David Gurley

AstraZeneca (United States)

Also Known As

D A Gurley, D Gurley, D. A. Gurley, D. Gurley, David A Gurley, David A. Gurley, David Gurley, David A. Gurley

19

Publications

1.1K

Citations

15

H-Index

48

Concepts

All Affiliations

AstraZeneca (United States)Wilmington University Johns Hopkins University

DG

About

David Gurley is an author at AstraZeneca (United States) specializing in medicine, neuropharmacology, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	12	12	678
2	Social Sciences	8	8	410
3	Biochemistry	5	5	379
4	Cell Biology	4	4	203
5	Natural Sciences	1	1	141

David Gurley

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16

Publications

1.1K

Citations

15

H-Index

	Year	Citations
The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective α7 nicotinic receptor partial agonist John E. Macor, David Gurley, Thomas H. Lanthorn, Bioorganic & Medicinal Chemistry Letters	2001	157
Point mutations in the M2 region of the alpha, beta, or gamma subunit of the GABAA channel that abolish block by picrotoxin. David Gurley, Phil C. Ross, David S. Weiss, PubMed M2 RegionMolecular BiologyMolecular GeneticsGabaa SubunitsCellular Physiology	1995	141
(−)-Spiro[1-azabicyclo[2.2.2]octane-3,5‘-oxazolidin-2‘-one], a Conformationally Restricted Analogue of Acetylcholine, Is a Highly Selective Full Agonist at the α7 Nicotinic Acetylcholine Receptor G. B. MULLEN, James Napier, Michael Balestra, Journal of Medicinal Chemistry PharmacotherapySocial SciencesMolecular PharmacologyMedicinal ChemistryNeurochemistry	2000	132
Distinct Pharmacologic Properties of Neuromuscular Blocking Agents on Human Neuronal Nicotinic Acetylcholine Receptors Malin Jonsson Fagerlund, David Gurley, Michael Dabrowski, Anesthesiology	2006	101
Selective α7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes S G Sydserff, Evelynjeane J. Sutton, Dekun Song, Biochemical Pharmacology Cognitive ScienceBrain FunctionSynaptic SignalingMedicineNicotine	2009	96
α subunits influence Zn block of γ2 containing GABAA receptor currents Gentry White, David Gurley Neuroreport	1995	65
EEG-β/γ spectral power elevation in rat: a translatable biomarker elicited by GABA<sub>Aα2/3</sub>-positive allosteric modulators at nonsedating anxiolytic doses Edward P. Christian, Dean H. Snyder, Wei Song, Journal of Neurophysiology NeurotransmitterNeuromodulation TherapiesNeurophysiological BiomarkersNeurochemical BiomarkersSocial Sciences	2014	63
Activation and Inhibition of Human Muscular and Neuronal Nicotinic Acetylcholine Receptors by Succinylcholine Malin Jonsson Fagerlund, Michael Dabrowski, David Gurley, Anesthesiology	2006	58
Development and SAR of functionally selective allosteric modulators of GABAA receptors Cristóbal Alhambra, Chris Becker, Timothy J. Blake, Bioorganic & Medicinal Chemistry Selective Allosteric ModulatorsSignal TransductionBiochemistryFunctional SelectivityMedicine	2011	51
Nicotinic agonists competitively antagonize serotonin at mouse 5-HT3 receptors expressed in Xenopus oocytes David Gurley, Thomas H. Lanthorn Neuroscience Letters 5-Ht3 ReceptorsMolecular PharmacologyXenopus OocytesSignal TransductionMedicine	1998	50

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