Karen K. Cook

Discovery and Structure−Activity Relationship of Quinuclidine Benzamides as Agonists of α7 Nicotinic Acetylcholine Receptors

Alice L. Bodnar, Luz Cortes-Burgos, Karen K. Cook et al. · Journal of Medicinal Chemistry · 2005 · 214 citations · Full text

Pharmacotherapy, Chemical Biology, Molecular Pharmacology +19

Discovery of<i>N</i>-[(3<i>R</i>)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-<i>c</i>]pyridine-5-carboxamide, an Agonist of the α7 Nicotinic Acetylcholine Receptor, for the Potential Treatment of Cognitive Deficits in Schizophrenia:  Synthesis and Structure−Activity Relationship

Donn G. Wishka, Daniel P. Walker, Karen M. Yates et al. · Journal of Medicinal Chemistry · 2006 · 188 citations · Full text

Neuropsychology, Compound 14, Psychopharmacology +23

Two Adaptor Proteins Differentially Modulate the Phosphorylation and Biophysics of Kv1.3 Ion Channel by Src Kinase

Karen K. Cook, Debra Ann Fadool · Journal of Biological Chemistry · 2002 · 74 citations · Full text

Discovery of 4-(5-Methyloxazolo[4,5-<i>b</i>]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a Novel α7 Nicotinic Acetylcholine Receptor Agonist for the Treatment of Cognitive Disorders in Schizophrenia: Synthesis, SAR Development, and in Vivo Efficacy in Cognition Models

Christopher J. O’Donnell, Bruce N. Rogers, Brian S. Bronk et al. · Journal of Medicinal Chemistry · 2009 · 73 citations · Full text