Stereoselective titanium-mediated syn -aldol reaction from a lactate-derived chiral ethyl ketone

Double Asymmetric Synthesis and a New Strategy for Stereochemical Control in Organic Synthesis

Satoru Masamune, William Choy, John S. Petersen et al. · Angewandte Chemie International Edition in English · 1985 · 1.1K citations

Natural Sciences, Chemistry, Carbohydrate Chemistry +14

Asymmetric Aldol Additions:  Use of Titanium Tetrachloride and (−)-Sparteine for the Soft Enolization of <i>N-</i>Acyl Oxazolidinones, Oxazolidinethiones, and Thiazolidinethiones

Michael T. Crimmins, Bryan W. King, Elie A. Tabet et al. · The Journal of Organic Chemistry · 2001 · 384 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11

Acyclic diastereoselective synthesis using tartrate ester-modified crotylboronates. Double asymmetric reactions with .alpha.-methyl chiral aldehydes and synthesis of the C(19)-C(29) segment of rifamycin S

William Roush, Alan D. Palkowitz, Kaori Ando · Journal of the American Chemical Society · 1990 · 273 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

Acyclic stereoselection. 54. Extending the scope of the Evans asymmetric aldol reaction: preparation of anti and "non-Evans" syn aldols

Michael A. Walker, Clayton H. Heathcock · The Journal of Organic Chemistry · 1991 · 234 citations

Natural Sciences, Chemistry, Lead Optimization +7

Asymmetric Aldol Additions with Titanium Enolates of Acyloxazolidinethiones:  Dependence of Selectivity on Amine Base and Lewis Acid Stoichiometry

Michael T. Crimmins, Bryan W. King, Elie A. Tabet · Journal of the American Chemical Society · 1997 · 224 citations

Natural Sciences, Chemistry, Catalysis +12