Concepedia

Discovery of a potent and selective series of pyrazole bacterial methionyl-tRNA synthetase inhibitors

John Finn, Karen Mattia, Mike Morytko, Siya Ram, Yingfei Yang, Ximao Wu, Elsa Mak, Paul Gallant, Dennis D. Keith

Bioorganic & Medicinal Chemistry Letters · 2003 · 75 citations · 12 references

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References

12

Effects of Cigarette Smoking on Lung Function in Adolescent Boys and Girls

Diane R. Gold, Xiaobin Wang, David Wypij et al. · New England Journal of Medicine · 1996 · 595 citations · Full text

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Interaction of pseudomonic acid A with <i>Escherichia coli</i> B isoleucyl-tRNA synthetase

Julia Hughes, G. Mellows · Biochemical Journal · 1980 · 188 citations · Full text

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Aminoacyl tRNA synthetases as targets for new anti‐infectives

Paul Schimmel, Jianshi Tao, Jason M. Hill · The FASEB Journal · 1998 · 166 citations

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On the mode of action of pseudomonic acid: Inhibition of protein synthesis in Staphylococcus aureus.

Julia Hughes, G. Mellows · The Journal of Antibiotics · 1978 · 115 citations

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Nanomolar Inhibitors of <i>Staphylococcus </i><i>a</i><i>ureus</i> Methionyl tRNA Synthetase with Potent Antibacterial Activity against Gram-Positive Pathogens

Richard L. Jarvest, John M. Berge, Valerie Berry et al. · Journal of Medicinal Chemistry · 2002 · 102 citations · Full text

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