Concepedia

One-pot diastereoselective synthesis of new racemic and achiral spirohydantoins

Nosrat O. Mahmoodi, Ziba Khodaee

Mendeleev Communications · 2004 · 21 citations · 12 references

DOI

Concepts

Abstract

An efficient and versatile method was used for the diastereoselective synthesis of achiral and racemic spirohydantoins based on ketones 4, 5, 7 and 10.

References

12

S-Glucosylated hydantoins as new antiviral agents

A. A. EL‐BARBARY, Ahmed I. Khodair, Erik B. Pedersen et al. · Journal of Medicinal Chemistry · 1994 · 129 citations

, , +9

Spiro Hydantoin Aldose Reductase Inhibitors

Reinhard Sarges, Rodney C. Schnur, John L. Belletire et al. · Journal of Medicinal Chemistry · 1988 · 97 citations · Full text

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Diethyl 2,4-dioxoimidazolidine-5-phosphonates: Horner-Wadsworth-Emmons reagents for the mild and efficient preparation of C-5 unsaturated hydantoin derivatives

Nicholas A. Meanwell, Herbert R. Roth, Edward C. Smith et al. · The Journal of Organic Chemistry · 1991 · 69 citations

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5,5-Disubstituted hydantoins: syntheses and anti-HIV activity

Rob Comber, Robert C. Reynolds, Joyce D. Friedrich et al. · Journal of Medicinal Chemistry · 1992 · 67 citations

, , +12

Effects of log <i>P</i> and Phenyl Ring Conformation on the Binding of 5-Phenylhydantoins to the Voltage-Dependent Sodium Channel

Milton L. Brown, George Bosworth Brown, Wayne J. Brouillette · Journal of Medicinal Chemistry · 1997 · 59 citations · Full text

, , +16