Edward C. Smith

Synthesis and Activity of New Aryl- and Heteroaryl-Substituted Pyrazole Inhibitors of the Transforming Growth Factor-β Type I Receptor Kinase Domain

J. Scott Sawyer, Bryan D. Anderson, Douglas W. Beight et al. · Journal of Medicinal Chemistry · 2003 · 237 citations · Full text

Drug Target, Pyrazole-based Inhibitors, Pharmaceutical Chemistry +20

Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-β type I receptor kinase domain

J. Scott Sawyer, Douglas W. Beight, Karen S. Britt et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 161 citations

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Chemistry +9

Stereoselectivity and mode of inhibition of phosphoinositide-coupled excitatory amino acid receptors by 2-amino-3-phosphonopropionic acid.

Darryle D. Schoepp, Bryan G. Johnson, Edward C. Smith et al. · Molecular Pharmacology · 1990 · 102 citations

Synthesis and biological activity of structural analogs of the anticancer benzophenanthridine alkaloid nitidine chloride

Mark Cushman, Prem Mohan, Edward C. Smith · Journal of Medicinal Chemistry · 1984 · 74 citations

Diethyl 2,4-dioxoimidazolidine-5-phosphonates: Horner-Wadsworth-Emmons reagents for the mild and efficient preparation of C-5 unsaturated hydantoin derivatives

Nicholas A. Meanwell, Herbert R. Roth, Edward C. Smith et al. · The Journal of Organic Chemistry · 1991 · 68 citations

Medicinal Chemistry, Derivative (Chemistry), Bioorganic Chemistry +13