Concepedia

Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity

Dimitrios Galanakis, Angeliki P. Kourounakis, Karyophyllis C. Tsiakitzis, Christos M. Doulgkeris, Eleni A. Rekka, Antonios Gavalas, Constantina Kravaritou, Christos Charitos, Panos N. Kourounakis

Bioorganic & Medicinal Chemistry Letters · 2004 · 77 citations · 22 references

DOI

Concepts

References

22

Free radicals in biology and medicine

General Pharmacology The Vascular System · 1991 · 17.2K citations

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Risk of Alzheimer's disease and duration of NSAID use

Walter F. Stewart, Claudia H. Kawas, María M. Corrada et al. · Neurology · 1997 · 1.1K citations · Full text

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Clinical trial of indomethacin in Alzheimer's disease

Jospeh Rogers, L. Kirby, S. R. Hempelman et al. · Neurology · 1993 · 999 citations

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Sulfhydryl Compounds May Mediate Gastric Cytoprotection

Sándor Szabó, Jerry S. Trier, Paul W. Frankel · Science · 1981 · 460 citations

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Ester and Amide Derivatives of the Nonsteroidal Antiinflammatory Drug, Indomethacin, as Selective Cyclooxygenase-2 Inhibitors

Amit S. Kalgutkar, Alan B. Marnett, Brenda C. Crews et al. · Journal of Medicinal Chemistry · 2000 · 312 citations · Full text

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