PEDIATRICS · 2010 · 22 citations · 18 references
Public HealthChild HealthPediatricsChild NutritionInfant HealthPediatric NutritionBottle FeedingChild Health PreventionInfant Feeding PracticesIron DeficiencyIron Deficiency DisordersIron NutritionBottle Feeding EducationEducational Intervention EvaluationFerritin ElevationFerritin StatusIron Deficiency In InfancyIron Status In InfancyMilk ConsumptionRoutine Health Maintenance
OBJECTIVE: The goal was to determine whether an office-based, educational intervention for parents of 9-month-old children could reduce bottle use and iron depletion at 2 years of age. METHODS: Between January 2006 and 2007, 251 healthy, 9-month-old infants attending a routine health maintenance visit were assigned randomly to intervention or control groups. Parents in the intervention group were introduced to a 1-week protocol to wean their children from the bottle. Iron depletion (ferritin levels of <10 microg/L) and bottle use at 2 years were assessed. RESULTS: A total of 201 children were monitored to 2 years of age (follow-up rate: 81%). Rates of iron depletion (10 [10%] of 102 children vs 13 [13%] of 99 children; P = .42) and milk consumption of >16 oz (16 [16%] of 102 children vs 17 [17%] of 99 children; P = .7) were not significantly different between the 2 groups at 2 years of age. However, children in the intervention group started using a cup 3 months earlier (9 vs 12 months; P = .001), were weaned from the bottle 4 months earlier (12 vs 16 months; P = .004), and were more than one-half as likely to be using a bottle at 2 years of age (15 [15%] of 102 children vs 39 [40%] of 99 children; P = .0004). CONCLUSIONS: This simple intervention administered during a health maintenance visit did not result in a decrease in iron depletion at 2 years of age but did result in a 60% reduction in prolonged bottle use.
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Improving the reporting of pragmatic trials: an extension of the CONSORT statement
Merrick Zwarenstein, Shaun Treweek, Joel Gagnier et al. · BMJ · 2008 · 1.8K citations · Full text
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