Concepedia

Publication | Closed Access

Macrophage Mitochondrial Energy Status Regulates Cholesterol Efflux and Is Enhanced by Anti-miR33 in Atherosclerosis

DOI

177

Citations

33

References

2015

Year

Denuja Karunakaran, A. Brianne Thrush, My-Anh Nguyen, Laura M. Richards, Michèle Geoffrion, Ragunath Singaravelu, Eleni Ramphos, Prakriti Shangari, Mireille Ouimet, John Paul Pezacki,
Circulation Research

Abstract

This study demonstrates that anti-miR33 therapy derepresses genes that enhance mitochondrial respiration and ATP production, which in conjunction with increased ABCA1 expression, works to promote macrophage cholesterol efflux and reduce atherosclerosis.

References

YearCitations

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