Concepedia

The Transcription Factor IRF8 Activates Integrin-Mediated TGF-β Signaling and Promotes Neuroinflammation

Yuko Yoshida, Ryusuke Yoshimi, Hiroaki Yoshii, Daniel H. Kim, Anup Dey, Huabao Xiong, Jeeva Munasinghe, Itaru Yazawa, Michael J. O’Donovan, Olga A. Maximova,

Immunity · 2014 · 148 citations · 44 references

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44

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Estelle Bettelli, Yijun Carrier, Wenda Gao et al. · Nature · 2006 · 6.9K citations

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The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou et al. · Cell · 2006 · 5.1K citations · Full text

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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

Heon Park, Zhaoxia Li, Xuexian O. Yang et al. · Nature Immunology · 2005 · 4.2K citations · Full text

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

Jonathan Sherlock, Yi Chen, Craig A. Murphy et al. · Nature · 2003 · 2.9K citations

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Conditional gene targeting in macrophages and granulocytes using LysMcre mice

Björn E. Clausen, Christoph Burkhardt, Walter Reith et al. · Transgenic Research · 1999 · 2.2K citations

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