Concepedia

Chemometric and chemoinformatic analyses of anabolic and androgenic activities of testosterone and dihydrotestosterone analogues

Yoanna María Álvarez-Ginarte, Rachel Crespo‐Otero, Yovani Marrero‐Ponce, Pedro Noheda, José M. Garcı́a de la Vega, Luís A. Montero, José Alberto Ruiz García, José Caldera-Luzardo, Ysaías J. Alvarado

Bioorganic & Medicinal Chemistry · 2008 · 11 citations · 30 references

Concepts

Life SciencesBiochemistryPharmacologyDrug DiscoverySteroid BiochemistryStructure-activity RelationshipsGonadal HormonesGonadal Steroid HormonesGonadal SteroidogenesisHormone MetabolismSteroid Hormone BiochemistrySteroid Metabolism5 Alpha-reductaseAnabolic Androgenic SteroidsAnabolic HormonesAndrogen MetabolismAndrogen MetabolitesAndrogen PharmacologyAromatase Activity

References

30

Electrophilicity Index

Robert G. Parr, László von Szentpály, Shubin Liu · Journal of the American Chemical Society · 1999 · 7.3K citations

Natural Sciences, Chemistry, Organic Chemistry +3

Optimization of parameters for semiempirical methods II. Applications

James J. P. Stewart · Journal of Computational Chemistry · 1989 · 3.7K citations

Natural Sciences, Chemistry, Computational Chemistry +9

Alexander Golbraikh, Alexander Tropsha · Journal of Molecular Graphics and Modelling · 2002 · 3.7K citations

Principles of QSAR models validation: internal and external

Paola Gramatica · QSAR & Combinatorial Science · 2007 · 2.2K citations · Full text

Pharmacy, Medicinal Chemistry, Drug Design +13

Comprehensive medicinal chemistry

H. Timmerman, Aalt Bast, H. van der Goot et al. · Trends in Pharmacological Sciences · 1991 · 1.2K citations