Concepedia

Aromatase Activity

Aromatase Activity is the enzymatic activity of the cytochrome P450 aromatase (CYP19A1) that catalyzes the conversion of androgens, primarily testosterone and androstenedione, into estrogens, specifically estradiol and estrone, through a series of hydroxylation and aromatization reactions, thereby serving as a key regulatory step in gonadal steroidogenesis.

4.8K

Publications

262.2K

Citations

15.2K

Authors

2.9K

Institutions

Publications per year

2017–2026

411

Parents

Publications

4.8K

Persistent DDT metabolite p,p'–DDE is a potent androgen receptor antagonist

William Kelce, Christy R. Stone, Susan Laws et al. · Nature · 1995 · 1.5K citations

, , +16

Endocrine Therapy plus Zoledronic Acid in Premenopausal Breast Cancer

Michael Gnant, Brigitte Mlineritsch, Walter Schippinger et al. · New England Journal of Medicine · 2009 · 1K citations · Full text

, , +13

Source of Estrogen Production in Postmenopausal Women1

Jerrold Grodin, Pentti K. Siiteri, Paul C. MacDonald · The Journal of Clinical Endocrinology & Metabolism · 1973 · 963 citations

, , +16

Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the <i>cyp19</i> gene

Carolyn R. Fisher, Kathy H. Graves, Albert F. Parlow et al. · Proceedings of the National Academy of Sciences · 1998 · 856 citations · Full text

, , +17

Decreases in Ovarian Cytochrome P450c17α Activity and Serum Free Testosterone after Reduction of Insulin Secretion in Polycystic Ovary Syndrome

John E. Nestler, Daniela Jakubowicz · New England Journal of Medicine · 1996 · 750 citations · Full text

, , +17

1–5 of 4.8K

Authors

15.2K

  1. NH
    Nobuhiro Harada

    Fujita Health University, Japan

    81 publications · 6.4K citations

    45

    h-index

  2. ER
    Evan R. Simpson

    The University of Texas Southwestern Medical Center, United States

    72 publications · 6.8K citations

    43

    h-index

  3. JB
    Jacques Balthazart

    University of Liège, Belgium

    64 publications · 4.1K citations

    40

    h-index

  4. MD
    Mitch Dowsett

    Royal Marsden Hospital, United Kingdom

    56 publications · 4.6K citations

    35

    h-index

  5. SE
    Serdar E. Bulun

    Northwestern University, United States

    45 publications · 4.3K citations

    34

    h-index

1–5 of 15.2K

Institutions

2.9K

  1. The University of Texas Southwestern Medical Center

    Dallas, United States

    62 h-index

    414 publications

    52.4K citations

  2. University of Liège

    Liège, Belgium

    50 h-index

    234 publications

    14K citations

  3. Fujita Health University

    Toyoake, Japan

    46 h-index

    150 publications

    11.4K citations

  4. University of Maryland, Baltimore

    Baltimore, United States

    45 h-index

    253 publications

    17.8K citations

  5. City of Hope

    Lancaster, United States

    39 h-index

    189 publications

    12.7K citations

  6. Tohoku University

    Sendai, Japan

    36 h-index

    314 publications

    16.4K citations

  7. Oregon Health & Science University

    Portland, United States

    36 h-index

    158 publications

    12.8K citations

  8. Beckman Research Institute

    Duarte, United States

    35 h-index

    181 publications

    11.9K citations

1–8 of 2.9K

Venues

  1. Endocrinology

    277 publications · 21.4K citations

    83

    h-index

  2. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 246 publications · 21K citations

    79

    h-index

  3. 67

    h-index

  4. PubMed

    Repository · 203 publications · 9.2K citations

    53

    h-index

  5. General and Comparative Endocrinology

    99 publications · 5.3K citations

    47

    h-index

1–5