Concepedia

5 Alpha-reductase

5 Alpha-Reductase is a steroidogenic enzyme that catalyzes the irreversible conversion of testosterone to dihydrotestosterone by reducing the double bond between carbon atoms 4 and 5 in the steroid A-ring, thereby serving a critical role in androgen biosynthesis and signaling.

1.8K

Publications

96K

Citations

6.7K

Authors

1.6K

Institutions

Publications per year

2017–2026

186

Variants

3-Oxo-5α-steroid 4-Dehydrogenase5α-Reductase

Parents

Publications

1.8K

The Influence of Finasteride on the Development of Prostate Cancer

Ian M. Thompson, Phyllis J. Goodman, Catherine M. Tangen et al. · New England Journal of Medicine · 2003 · 2.5K citations · Full text

, , +14

The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia

John D. McConnell, Claus G. Roehrborn, Oliver Bautista et al. · New England Journal of Medicine · 2003 · 2K citations · Full text

, , +14

Steroid 5α-Reductase Deficiency in Man: An Inherited Form of Male Pseudohermaphroditism

Julianne Imperato‐McGinley, Luis Guerrero, Teófilo Gautier et al. · Science · 1974 · 1.3K citations

, , +17

The Effect of Finasteride in Men with Benign Prostatic Hyperplasia

Glenn J. Gormley, Elizabeth Stoner, Reginald C. Bruskewitz et al. · New England Journal of Medicine · 1992 · 1.1K citations · Full text

, , +17

A Role for Brassinosteroids in Light-Dependent Development of <b> <i>Arabidopsis</i> </b>

Jianming Li, Punita Nagpal, Véronique Vitart et al. · Science · 1996 · 863 citations

, , +17

1–5 of 1.8K

Authors

6.7K

  1. JI
    Julianne Imperato‐McGinley

    Cornell University, United States

    46 publications · 7.1K citations

    36

    h-index

  2. DW
    David W. Russell

    The University of Texas Southwestern Medical Center, United States

    34 publications · 5.9K citations

    30

    h-index

  3. JD
    Jean D. Wilson

    The University of Texas Southwestern Medical Center, United States

    26 publications · 2.9K citations

    25

    h-index

  4. RS
    Roger S. Rittmaster

    Dalhousie University, Canada

    24 publications · 2.1K citations

    21

    h-index

  5. TG
    Teófilo Gautier

    Cornell University, United States

    17 publications · 3.4K citations

    17

    h-index

1–5 of 6.7K

Institutions

1.6K

  1. The University of Texas Southwestern Medical Center

    Dallas, United States

    55 h-index

    196 publications

    32.2K citations

  2. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    37 h-index

    260 publications

    35.1K citations

  3. Cornell University

    Ithaca, United States

    35 h-index

    190 publications

    18.1K citations

  4. University of Southern California

    Los Angeles, United States

    23 h-index

    107 publications

    5.8K citations

  5. University of Milan

    Milan, Italy

    23 h-index

    137 publications

    6.5K citations

  6. Harvard University

    Cambridge, United States

    20 h-index

    73 publications

    3.6K citations

  7. Research Triangle Park Foundation

    Durham, United States

    20 h-index

    66 publications

    6.8K citations

  8. McGill University

    Montreal, Canada

    20 h-index

    52 publications

    1.7K citations

1–8 of 1.6K

Venues

  1. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 131 publications · 9.3K citations

    58

    h-index

  2. Endocrinology

    107 publications · 7.2K citations

    53

    h-index

  3. PubMed

    Repository · 132 publications · 5.6K citations

    38

    h-index

  4. The Prostate

    54 publications · 2.8K citations

    30

    h-index

  5. The Journal of Urology

    46 publications · 2.1K citations

    29

    h-index

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