Concepedia

Investigating the Enteroenteric Recirculation of Apixaban, a Factor Xa Inhibitor: Administration of Activated Charcoal to Bile Duct-Cannulated Rats and Dogs Receiving an Intravenous Dose and Use of Drug Transporter Knockout Rats

Donglu Zhang, Charles Frost, Kan He, A. David Rodrigues, Xiaoli Wang, Lifei Wang, Theunis C. Goosen, W. Griffith Humphreys

Drug Metabolism and Disposition · 2013 · 62 citations · 49 references

DOI

Concepts

References

49

Apixaban versus Warfarin in Patients with Atrial Fibrillation

Christopher B. Granger, John H. Alexander, John J.V. McMurray et al. · New England Journal of Medicine · 2011 · 8.9K citations · Full text

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Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

F Thiébaut, T Tsuruo, Hironobu Hamada et al. · Proceedings of the National Academy of Sciences · 1987 · 2.8K citations · Full text

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Apixaban in Patients with Atrial Fibrillation

Stuart J. Connolly, John W. Eikelboom, Campbell Joyner et al. · New England Journal of Medicine · 2011 · 2.4K citations · Full text

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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

Alfred H. Schinkel, Jasper Smit, Olaf van Tellingen et al. · Cell · 1994 · 2.3K citations

, , +14

Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues.

Marc Maliepaard, George L. Scheffer, Ian F. Faneyte et al. · PubMed · 2001 · 1.1K citations

, , +14