Concepedia

Transporter Knockout Models

Transporter Knockout Models is a genetic engineering approach in which specific renal transporter genes are deliberately inactivated to elucidate their physiological roles by observing resultant alterations in solute and fluid handling.

44

Publications

2.2K

Citations

332

Authors

119

Institutions

Publications per year

2017–2026

15

Parents

Publications

44

Renal and intestinal transport defects in Slc26a6-null mice

Zhaohui Wang, Tong Wang, Snežana Petrović et al. · American Journal of Physiology-Cell Physiology · 2004 · 183 citations

, , +17

Overlapping in vitro and in vivo specificities of the organic anion transporters OAT1 and OAT3 for loop and thiazide diuretics

Volker Vallon, Timo Rieg, Sun-Young Ahn et al. · American Journal of Physiology-Renal Physiology · 2008 · 131 citations

, , +15

Mouse model of type II Bartter's syndrome. II. Altered expression of renal sodium- and water-transporting proteins

Carsten A. Wagner, Dominique Loffing‐Cueni, Qingshang Yan et al. · American Journal of Physiology-Renal Physiology · 2008 · 114 citations

, , +17

Alterations in transporter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1α

Jonathan Maher, Angela L. Slitt, T.N. Callaghan et al. · Biochemical Pharmacology · 2006 · 105 citations

, , +15

Substrate Overlap between Mrp4 and Abcg2/Bcrp Affects Purine Analogue Drug Cytotoxicity and Tissue Distribution

Kazumasa Takenaka, George L. Scheffer, Masashi Adachi et al. · Cancer Research · 2007 · 100 citations

, , +14

1–5 of 44

Authors

332

  1. MO
    Mona Oppermann

    National Institute of Diabetes and Digestive and Kidney Diseases, United States

    2 publications · 174 citations

    2

    h-index

  2. ML
    Min Li

    Peking University, China

    2 publications · 58 citations

    2

    h-index

  3. HC
    Hayo Castrop

    University of Regensburg, Germany

    2 publications · 174 citations

    2

    h-index

  4. HZ
    Hong Zhou

    Peking University, China

    2 publications · 58 citations

    2

    h-index

  5. FL
    Florian Läng

    University of Tübingen, Germany

    2 publications · 56 citations

    2

    h-index

1–5 of 332

Institutions

119

  1. National Institutes of Health

    Bethesda, United States

    4 h-index

    20 publications

    1.8K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    20 publications

    1.7K citations

  3. University of California San Diego

    San Diego, United States

    3 h-index

    12 publications

    418 citations

  4. Mayo Clinic

    Rochester, United States

    2 h-index

    2 publications

    65 citations

  5. Nagoya University

    Nagoya, Japan

    2 h-index

    2 publications

    61 citations

  6. Centre for Biomedical Network Research on Rare Diseases

    Madrid, Spain

    2 h-index

    7 publications

    169 citations

  7. Swiss Integrative Center for Human Health

    Fribourg, Switzerland

    2 h-index

    7 publications

    228 citations

  8. University of Campania "Luigi Vanvitelli"

    Caserta, Italy

    2 h-index

    6 publications

    202 citations

1–8 of 119

Venues

  1. 6

    h-index

  2. Journal of Biological Chemistry

    JBC · 3 publications · 135 citations

    3

    h-index

  3. Journal of the American Society of Nephrology

    3 publications · 213 citations

    3

    h-index

  4. Drug Metabolism and Disposition

    2 publications · 76 citations

    2

    h-index

  5. Biochemical and Biophysical Research Communications

    BBRC · 2 publications · 89 citations

    2

    h-index

1–5