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Publication | Open Access

Sensitization of Pancreatic Cancer to Chemoradiation by the Chk1 Inhibitor MK8776

DOIFull Paper Access

102

Citations

30

References

2013

Year

Carl G. Engelke, Leslie A. Parsels, Yushen Qian, Qiang Zhang, David Karnak, Jordan R. Robertson, Daria M. Tanska, Dongping Wei, Mary A. Davis, Joshua D. Parsels,
Clinical Cancer Research

Abstract

Together, our results suggest that MK8776 selectively sensitizes HRR-proficient pancreatic cancer cells and xenografts to gemcitabine-radiation and support the clinical investigation of MK8776 in combination with gemcitabine-radiation in locally advanced pancreatic cancer.

References

YearCitations

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