Overactivated Neddylation Pathway as a Therapeutic Target in Lung Cancer

Lihui Li, Mingsong Wang, Guangyang Yu, +24

JNCI Journal of the National Cancer Institute

Radiosensitization of Human Pancreatic Cancer Cells by MLN4924, an Investigational NEDD8-Activating Enzyme Inhibitor

Dongping Wei, Hua Li, Jie Yu, +6

Cancer Research

Tumor BiologyOncologyPancreatic CancerSeveral Scf SubstratesOncogenic Agent +9

Combined Inhibition of Wee1 and PARP1/2 for Radiosensitization in Pancreatic Cancer

David Karnak, Carl G. Engelke, Leslie A. Parsels, +9

Clinical Cancer Research

Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair

Dongping Wei, Leslie A. Parsels, David Karnak, +8

Clinical Cancer Research

Sensitization of Pancreatic Cancer to Chemoradiation by the Chk1 Inhibitor MK8776

Carl G. Engelke, Leslie A. Parsels, Yushen Qian, +12

Clinical Cancer Research

Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis

Hua Li, Mingjia Tan, Lijun Jia, +8

Journal of Clinical Investigation

Lung InflammationCell DeathMtor PathwaysCancer BiologyTumor Biology +18

Tumor‐targeting <i>Salmonella typhimurium</i> improves cyclophosphamide chemotherapy at maximum tolerated dose and low‐dose metronomic regimens in a murine melanoma model

Lijun Jia, Dongping Wei, Qi‐Ming Sun, +4

International Journal of Cancer

Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis

Xiufang Xiong, Yongchao Zhao, Fei Tang, +6

eLife

PathologyCell DeathP53 RegulationCancer BiologyPhysiological Regulator +15

Oral delivery of tumor‐targeting <i>Salmonella</i> for cancer therapy in murine tumor models

Lijun Jia, Dongping Wei, Qi‐Ming Sun, +3

Cancer Science

The Neddylation-Cullin 2-RBX1 E3 Ligase Axis Targets Tumor Suppressor RhoB for Degradation in Liver Cancer

Junfeng Xu, Lihui Li, Guangyang Yu, +14

Molecular & Cellular Proteomics

Liver CarcinogenesisCancer BiologyNeddylation-cullin-ring E3 LigaseTumor BiologyRadiation Oncology +15