Concepedia

Author

Leslie A. Parsels

University of MichiganORCID

Also Known As

L A Parsels, L.A. Parsels, Leslie A Parsels, Leslie A. Parsels, Leslie Anne Parsels, Leslie Parsels, Leslie A Parsels, Parsels, Leslie A.

153

Publications

2.7K

Citations

25

H-Index

50

Concepts

All Affiliations

University of MichiganU-M Rogel Cancer CenterMichigan Center for Translational PathologyAstraZeneca (United States)Radiation Oncology Associates
LA

About

Leslie A. Parsels is an author at University of Michigan specializing in medicine, cell biology, and tumor biology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

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944

2

Cell Biology

7

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860

3

Health Sciences

1

1

84

4

Natural Sciences

1

1

17

5

Public Health

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132

Leslie A. Parsels

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30

Publications

2.5K

Citations

23

H-Index

YearCitations

Mechanism of Radiosensitization by the Chk1/2 Inhibitor AZD7762 Involves Abrogation of the G2 Checkpoint and Inhibition of Homologous Recombinational DNA Repair

Meredith A. Morgan, Leslie A. Parsels, Lili Zhao,

Cancer Research

2010

296

Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy

Qiang Zhang, Michael D. Green, Xueting Lang,

Cancer Research

2019

234

Dose Escalation Trial of the Wee1 Inhibitor Adavosertib (AZD1775) in Combination With Gemcitabine and Radiation for Patients With Locally Advanced Pancreatic Cancer

Kyle C. Cuneo, Meredith A. Morgan, Vaibhav Sahai,

Journal of Clinical Oncology

2019

190

Combined Inhibition of Wee1 and PARP1/2 for Radiosensitization in Pancreatic Cancer

David Karnak, Carl G. Engelke, Leslie A. Parsels,

Clinical Cancer Research

2014

150

Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells

Leslie A. Parsels, Meredith A. Morgan, Daria M. Tanska,

Molecular Cancer Therapeutics

2009

144

PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors

Leslie A. Parsels, David Karnak, Joshua D. Parsels,

Molecular Cancer Research

2017

136

Transient transfection studies of secretion in bovine chromaffin cells and PC12 cells. Generation of kainate-sensitive chromaffin cells

Peter Wick, Ruth A. Senter, Leslie A. Parsels,

Journal of Biological Chemistry

1993

132

The Combination of Epidermal Growth Factor Receptor Inhibitors with Gemcitabine and Radiation in Pancreatic Cancer

Meredith A. Morgan, Leslie A. Parsels, L.E. Kollar,

Clinical Cancer Research

2008

121

Role of Checkpoint Kinase 1 in Preventing Premature Mitosis in Response to Gemcitabine

Meredith A. Morgan, Leslie A. Parsels, Joshua D. Parsels,

Cancer Research

2005

105

Inhibition of Protein Phosphatase 2A Radiosensitizes Pancreatic Cancers by Modulating CDC25C/CDK1 and Homologous Recombination Repair

Dongping Wei, Leslie A. Parsels, David Karnak,

Clinical Cancer Research

2013

102

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