An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

William A. Devane, Aviva Breuer, Roger G. Pertwee et al. · Science · 1992 · 5.6K citations

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Molecular characterization of a peripheral receptor for cannabinoids

Sean Munro, Kerrie L. Thomas, Muna Abu-Shaar · Nature · 1993 · 5.1K citations

Medicine, Molecular Biology, Pharmacology +14

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

Raphael Mechoulam, Shimon Ben‐Shabat, L Hanŭs et al. · Biochemical Pharmacology · 1995 · 2.9K citations

Life Sciences, Pharmacology, Veterinary Pharmacology +10

2-Arachidonoylgylcerol: A Possible Endogenous Cannabinoid Receptor Ligand in Brain

Takayuki Sugiura, Shigeru Kondo, Akihiro Sukagawa et al. · Biochemical and Biophysical Research Communications · 1995 · 2.2K citations

Medicine, Neuroscience, Pharmacology +9

Formation and inactivation of endogenous cannabinoid anandamide in central neurons

Vincenzo Di Marzo, Angelo Fontana, Hugues Cadas et al. · Nature · 1994 · 1.6K citations · Full text

Life Sciences, Neurobiology, Neuroscience +12