William A. Devane

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

William A. Devane, Aviva Breuer, Roger G. Pertwee et al. · Science · 1992 · 5.6K citations

Life Sciences, Neuroscience, Pharmacology +15

Determination and characterization of a cannabinoid receptor in rat brain.

William A. Devane, F A Dysarz, M R Johnson et al. · Molecular Pharmacology · 1988 · 2.4K citations

Medicine, Neuroscience, Pharmacology +12

Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction.

Christian C. Felder, Eileen M. Briley, J Axelrod et al. · Proceedings of the National Academy of Sciences · 1993 · 475 citations

Medicine, Neurobiology, Pharmacology +13

Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells.

Ken Mackie, William A. Devane, Bertil Hille · Molecular Pharmacology · 1993 · 362 citations

Life Sciences, Neurobiology, Pharmacology +16

Anandamide, an endogenous ligand of the cannabinoid receptor, induces hypomotility and hypothermia in vivo in rodents

Jacqueline N. Crawley, Rebecca L. Corwin, John K. Robinson et al. · Pharmacology Biochemistry and Behavior · 1993 · 236 citations

Medicine, Neuroscience, Pharmacology +9