Concepedia

Calcium Blocks Formation of Apoptosome by Preventing Nucleotide Exchange in Apaf-1

Qing Bao, Wenyun Lu, Joshua D. Rabinowitz, Yigong Shi

Molecular Cell · 2007 · 88 citations · 33 references

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33

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.3K citations · Full text

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Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3

Hua Zou, William J. Henzel, Xuesong Liu et al. · Cell · 1997 · 3.1K citations · Full text

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The expanding role of mitochondria in apoptosis.

X. Wang · PubMed · 2001 · 2.4K citations

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Cytotoxicity‐dependent APO‐1 (Fas/CD95)‐associated proteins form a death‐inducing signaling complex (DISC) with the receptor.

Frank Kischkel, Stefan Hellbardt, Iris Behrmann et al. · The EMBO Journal · 1995 · 2.1K citations · Full text

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An APAF-1·Cytochrome c Multimeric Complex Is a Functional Apoptosome That Activates Procaspase-9

Hua Zou, Yuchen Li, Xuesong Liu et al. · Journal of Biological Chemistry · 1999 · 2.1K citations · Full text

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