Generation of Human Inner Ear Prosensory-Like Cells Via Epithelial-to-Mesenchymal Transition

Abstract

The results reveal that sensory epithelial cells from the adult human inner ear can re-enter the cell cycle and adopt a stem/progenitor cell fate. The outcomes of this study may open avenues for human hair cell progenitor generation, which could potentially provide a novel stem cell-based replacement for hearing loss and other inner ear disorders.