Xuemei Luo

FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation

Jun Hu, Xing Liu, Shiyu Xia et al. · Nature Immunology · 2020 · 1K citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +5

Genomic hallmarks of localized, non-indolent prostate cancer

Michael Fraser, Veronica Y. Sabelnykova, Takafumi N. Yamaguchi et al. · Nature · 2017 · 624 citations

Urology, Cancer Genomics, Prostatic Disease +3

Spatial genomic heterogeneity within localized, multifocal prostate cancer

Paul C. Boutros, Michael Fraser, Nicholas J. Harding et al. · Nature Genetics · 2015 · 472 citations · Full text

Urology, Engineering, Spatial Genomic Heterogeneity +4

Integration of Genomic and Transcriptional Features in Pancreatic Cancer Reveals Increased Cell Cycle Progression in Metastases

Ashton A. Connor, Robert E. Denroche, Gun Ho Jang et al. · Cancer Cell · 2019 · 239 citations · Full text

Pancreatic Cancer, Cell Cycle Progression, Tumor Heterogeneity +8

A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

Wei Jiao, Gurnit Atwal, Paz Polak et al. · Nature Communications · 2020 · 230 citations · Full text