Statistics
Publications
29
Citations
7.2K
H-Index
22
Active since
2016
Shiyu Xia is an author at Boston Children's Hospital specializing in medicine, engineering, and cell biology.
Publications per year
2016–2024
29
29
Gasdermin E suppresses tumour growth by activating anti-tumour immunity
Zhibin Zhang, Ying Zhang, Shiyu Xia et al. · Nature · 2020 · 1.7K citations · Full text
The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages
Charles L. Evavold, Jianbin Ruan, Yunhao Tan et al. · Immunity · 2017 · 1.1K citations · Full text
Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death
Pontus Ørning, Dan Weng, Kristian K. Starheim et al. · Science · 2018 · 1K citations · Full text
FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation
Jun Hu, Xing Liu, Shiyu Xia et al. · Nature Immunology · 2020 · 1K citations · Full text
Molecular Pharmacology, Medicinal Chemistry, Biochemistry +5
Gasdermin D pore structure reveals preferential release of mature interleukin-1
Shiyu Xia, Zhibin Zhang, Venkat Giri Magupalli et al. · Nature · 2021 · 574 citations · Full text
1–5 of 29