Charles L. Evavold

The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages

Charles L. Evavold, Jianbin Ruan, Yunhao Tan et al. · Immunity · 2017 · 1.1K citations · Full text

Inflammation, Cytokine, Inflammatory Lung Disease +11

Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis

Rui Miao, Cong Jiang, Winston Chang et al. · Immunity · 2023 · 416 citations · Full text

Mitophagy, Mitochondrial Function, Mitochondrial Dynamic +10

Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway

Charles L. Evavold, Iva Hafner‐Bratkovič, Pascal Devant et al. · Cell · 2021 · 387 citations · Full text

Signal Transduction, Medicine, Immunology +5

HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation

Venkat Giri Magupalli, Roberto Negro, Yuzi Tian et al. · Science · 2020 · 363 citations · Full text

SCS macrophages suppress melanoma by restricting tumor-derived vesicle–B cell interactions

Ferdinando Pucci, Christopher Garris, Charles Pin‐Kuang Lai et al. · Science · 2016 · 329 citations · Full text