Generation of Retroviral Packaging and Producer Cell Lines for Large-Scale Vector Production and Clinical Application: Improved Safety and High Titer

Production of high-titer helper-free retroviruses by transient transfection.

Warren S. Pear, Garry P. Nolan, Martin Scott et al. · Proceedings of the National Academy of Sciences · 1993 · 2.3K citations

Life Sciences, Biotechnology, Molecular Genetics +14

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

Jay P. Morgenstern, Hartmut Land · Nucleic Acids Research · 1990 · 2.1K citations · Full text

Pharmacy, Pharmaceutics, Gene Delivery +15

Improved retroviral vectors for gene transfer and expression.

A. Dusty Miller, G J Rosman · PubMed · 1989 · 2K citations

Life Sciences, Biotechnology, Molecular Biology +16

Redesign of Retrovirus Packaging Cell Lines To Avoid Recombination Leading to Helper Virus Production

A. Dusty Miller, Carol Buttimore · Molecular and Cellular Biology · 1986 · 1.3K citations

Life Sciences, Biology, Molecular Biology +15

Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges.

Olivier Danos, Richard C. Mulligan · Proceedings of the National Academy of Sciences · 1988 · 895 citations · Full text

Life Sciences, Biology, Molecular Biology +13