Nicholas J. DePolo

VSV-G Pseudotyped Lentiviral Vector Particles Produced in Human Cells Are Inactivated by Human Serum

Nicholas J. DePolo, Joyce D. Reed, Philip L. Sheridan et al. · Molecular Therapy · 2000 · 215 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +14

Continuing coevolution of virus and defective interfering particles and of viral genome sequences during undiluted passages: virus mutants exhibiting nearly complete resistance to formerly dominant defective interfering particles

Nicholas J. DePolo, Cristina Giachetti, John J. Holland · Journal of Virology · 1987 · 92 citations · Full text

Life Sciences, Evolutionary Biology, Genetics +17

Generation of Retroviral Packaging and Producer Cell Lines for Large-Scale Vector Production and Clinical Application: Improved Safety and High Titer

Philip L. Sheridan, Mordechai Bodner, Andrea Lynn et al. · Molecular Therapy · 2000 · 68 citations · Full text

Life Sciences, Bioengineering, Biotechnology +17

The Resistance of Retroviral Vectors Produced from Human Cells to Serum Inactivation In Vivo and In Vitro Is Primate Species Dependent

Nicholas J. DePolo, Cataline E. Harkleroad, Mordechai Bodner et al. · Journal of Virology · 1999 · 48 citations · Full text

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +14

Evaluation of PCR and ELISA Assays for Screening Clinical Trial Subjects for Replication-Competent Retrovirus

Darlene Martineau, WOLFGANG M. KLUMP, James E. McCormack et al. · Human Gene Therapy · 1997 · 34 citations

Life Sciences, Biotechnology, Molecular Biology +14