Concepedia

Viral Vector Production

Viral Vector Production is a methodological framework in gene therapy manufacturing that entails the systematic generation of viral vectors through the controlled cultivation of genetically engineered host cells in bioreactor systems, distinguished by its reliance on optimized perfusion and single-use bioreactor technologies to ensure scalable, sterile, and high-titer vector output.

436

Publications

27.2K

Citations

2.1K

Authors

544

Institutions

Publications per year

2017–2026

127

Parents

Publications

436

A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells

Eric Campeau, Victoria E. Ruhl, Françis Rodier et al. · PLoS ONE · 2009 · 1K citations · Full text

, , +10

The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses

Robert K. Naviaux, Eugenia Costanzi, Martin Haas et al. · Journal of Virology · 1996 · 748 citations · Full text

, , +16

Novel Tools for Production and Purification of Recombinant Adenoassociated Virus Vectors

Dirk Grimm, Andrea Kern, Karola Rittner et al. · Human Gene Therapy · 1998 · 700 citations

, , +16

Adeno-associated virus vectors can be efficiently produced without helper virus

Takashi Matsushita, SS Elliger, CA Elliger et al. · Gene Therapy · 1998 · 495 citations

, , +11

Efficient Intracellular Assembly of Papillomaviral Vectors

Christopher B. Buck, Diana V. Pastrana, Douglas R. Lowy et al. · Journal of Virology · 2003 · 493 citations · Full text

, , +17

1–5 of 436

Authors

2.1K

  1. AK
    Amine Kamen

    Biotechnology Research Institute, Canada

    27 publications · 1.6K citations

    24

    h-index

  2. PM
    Paula M. Alves

    Instituto de Biologia Experimental e Tecnológica, Portugal

    16 publications · 565 citations

    13

    h-index

  3. MJ
    Manuel J.T. Carrondo

    Instituto de Biologia Experimental e Tecnológica, Portugal

    14 publications · 618 citations

    12

    h-index

  4. SY
    Seppo Ylä‐Herttuala

    University of Eastern Finland, Finland

    9 publications · 550 citations

    9

    h-index

  5. SZ
    Sergei Zolotukhin

    University of Florida, United States

    8 publications · 627 citations

    8

    h-index

1–5 of 2.1K

Institutions

544

  1. Biotechnology Research Institute

    Montreal, Canada

    15 h-index

    57 publications

    3.9K citations

  2. National Research Council Canada

    Ottawa, Canada

    14 h-index

    59 publications

    4.8K citations

  3. University College London

    London, United Kingdom

    13 h-index

    65 publications

    3.6K citations

  4. University of Florida

    Gainesville, United States

    13 h-index

    70 publications

    5.2K citations

  5. Universidade Nova de Lisboa

    Lisbon, Portugal

    12 h-index

    44 publications

    1.7K citations

  6. National Institutes of Health

    Bethesda, United States

    12 h-index

    54 publications

    1.8K citations

  7. Instituto de Biologia Experimental e Tecnológica

    Oeiras, Portugal

    11 h-index

    62 publications

    2.5K citations

  8. Indiana University – Purdue University Indianapolis

    Indianapolis, United States

    10 h-index

    44 publications

    1.1K citations

1–8 of 544

Venues

  1. Human Gene Therapy

    45 publications · 5K citations

    33

    h-index

  2. 25

    h-index

  3. Gene Therapy

    30 publications · 1.8K citations

    23

    h-index

  4. Journal of Virology

    JVI · 22 publications · 2.9K citations

    20

    h-index

  5. Molecular Therapy

    22 publications · 2.2K citations

    19

    h-index

1–5