Concepedia

Approximations of the target-mediated drug disposition model and identifiability of model parameters

Leonid Gibiansky, Ekaterina Gibiansky, Tarundeep Kakkar, Peiming Ma

Journal of Pharmacokinetics and Pharmacodynamics · 2008 · 264 citations · 5 references

DOI

Concepts

References

5

Enzyme kinetics; behavior and analysis of rapid equilibrium and steady state enzyme systems

International Journal of Biochemistry · 1994 · 3K citations

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Enzyme Kinetics Behavior and analysis of rapid equilibrium and steady state enzyme systems

H. Gutfreund · FEBS Letters · 1975 · 1.5K citations

, , +16

General Pharmacokinetic Model for Drugs Exhibiting Target-Mediated Drug Disposition

Donald E. Mager, William J. Jusko · Journal of Pharmacokinetics and Pharmacodynamics · 2001 · 587 citations

, , +14

Quasi-Equilibrium Pharmacokinetic Model for Drugs Exhibiting Target-Mediated Drug Disposition

Donald E. Mager, Wojciech Krzyżański · Pharmaceutical Research · 2005 · 222 citations

, , +12

A mechanism‐based binding model for the population pharmacokinetics and pharmacodynamics of omalizumab

Naoto Hayashi, Yuko Tsukamoto, William M. Sallas et al. · British Journal of Clinical Pharmacology · 2006 · 171 citations · Full text

, , +17