Resistin is elevated following traumatic joint injury and causes matrix degradation and release of inflammatory cytokines from articular cartilage in vitro

The hormone resistin links obesity to diabetes

Claire M. Steppan, Shannon T. Bailey, Savitha Bhat et al. · Nature · 2001 · 4.8K citations

Life Sciences, Biochemistry, Endocrinology +12

Infliximab (chimeric anti-tumour necrosis factor α monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial

Ravinder N. Maini, E. William St. Clair, Ferdinand C. Breedveld et al. · The Lancet · 1999 · 2.4K citations

Medicine, Pharmacology, Pharmacotherapy +17

A Trial of Etanercept, a Recombinant Tumor Necrosis Factor Receptor:Fc Fusion Protein, in Patients with Rheumatoid Arthritis Receiving Methotrexate

Michael E. Weinblatt, Joel M. Kremer, Arthur D. Bankhurst et al. · New England Journal of Medicine · 1999 · 2.1K citations · Full text

Life Sciences, Immunology, Pharmacotherapy +17

High prevalence of knee osteoarthritis, pain, and functional limitations in female soccer players twelve years after anterior cruciate ligament injury

Stefan Lohmander, Anna Hafsteinsson Östenberg, Martin Englund et al. · Arthritis & Rheumatism · 2004 · 1.5K citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +16

Osteoarthritis: New Insights

David T. Felson, Timothy E. McAlindon · Annals of Internal Medicine · 2002 · 1.1K citations

Medicine, Orthopaedic Surgery, Pharmacotherapy +9