Simon Blake

Injurious Mechanical Compression of Bovine Articular Cartilage Induces Chondrocyte Apoptosis

Andreas M. Loening, Ian E. James, Marc E. Levenston et al. · Archives of Biochemistry and Biophysics · 2000 · 365 citations

Mechanobiology, Musculoskeletal Research, Engineering +9

Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis

Alison M. Badger, Don E. Griswold, Rasesh Kapadia et al. · Arthritis & Rheumatism · 2000 · 219 citations

Proteoglycan degradation after injurious compression of bovine and human articular cartilage in vitro: Interaction with exogenous cytokines

Parth Patwari, Michael N. Cook, Michael A. DiMicco et al. · Arthritis & Rheumatism · 2003 · 176 citations

Potent and Selective Inhibition of Human Cathepsin K Leads to Inhibition of Bone Resorption In Vivo in a Nonhuman Primate

George B. Stroup, Michael W. Lark, Daniel F. Veber et al. · Journal of Bone and Mineral Research · 2001 · 153 citations

A highly potent inhibitor of cathepsin K (relacatib) reduces biomarkers of bone resorption both in vitro and in an acute model of elevated bone turnover in vivo in monkeys

Sanjay Kumar, Lauren Dare, Janice A. Vasko-Moser et al. · Bone · 2006 · 136 citations

Animal Physiology, Sclerostin, Bone Resorption +12