N-Myc Downstream-Regulated Gene 4 ( NDRG4 ): A Candidate Tumor Suppressor Gene and Potential Biomarker for Colorectal Cancer - Concepedia

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N-Myc Downstream-Regulated Gene 4 ( NDRG4 ): A Candidate Tumor Suppressor Gene and Potential Biomarker for Colorectal Cancer

DOI Full Paper Access

212

Citations

52

References

2009

Year

Veerle Melotte, Marjolein H.F.M. Lentjes, Sandra M. van den Bosch, Debby M.E.I. Hellebrekers, Joep P.J. de Hoon, Kathleen L.J. Daenen, Iris Partouns-Hendriks, Filip Stessels, Joost Louwagie, Kim M. Smits,

JNCI Journal of the National Cancer Institute

Abstract

NDRG4 is a candidate tumor suppressor gene in colorectal cancer whose expression is frequently inactivated by promoter methylation. NDRG4 promoter methylation is a potential biomarker for the noninvasive detection of colorectal cancer in stool samples.

References

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