Concepedia

DNA-PKcs is important for Akt activation and gemcitabine resistance in PANC-1 pancreatic cancer cells

Hao Hu, Yuanlong Gu, Qian Yi, Benshun Hu, Congyuan Zhu, Gaohe Wang, Jian‐Ping Li

Biochemical and Biophysical Research Communications · 2014 · 34 citations · 24 references

DOI

Concepts

References

24

Adjuvant Chemotherapy With Gemcitabine vs Observation in Patients Undergoing Curative-Intent Resection of Pancreatic Cancer

Helmut Oettle, Stefan Post, P. Neuhaus et al. · JAMA · 2007 · 2.4K citations

, , +13

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

Jacob Falck, Julia Coates, Stephen P. Jackson · Nature · 2005 · 1.2K citations

, , +13

Gemcitabine: metabolism, mechanisms of action, and self-potentiation.

William Plunkett, Peng Huang, Yi-Zheng Xu et al. · PubMed · 1995 · 756 citations

, , +6

Identification of a PKB/Akt Hydrophobic Motif Ser-473 Kinase as DNA-dependent Protein Kinase

Jianhua Feng, Jongsun Park, Peter Cron et al. · Journal of Biological Chemistry · 2004 · 490 citations · Full text

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A Targeted DNA-PKcs-Null Mutation Reveals DNA-PK-Independent Functions for KU in V(D)J Recombination

Yijie Gao, Jayanta Chaudhuri, Chengming Zhu et al. · Immunity · 1998 · 439 citations · Full text

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