Association of<i>CYP2C8, CYP3A4, CYP3A5</i>, and<i>ABCB1</i>Polymorphisms with the Pharmacokinetics of Paclitaxel

Abstract

This study indicates that the presently evaluated variant alleles in the CYP2C8, CYP3A4, CYP3A5, and ABCB1 genes do not explain the substantial interindividual variability in paclitaxel pharmacokinetics.