Concepedia

A modular flow reactor for performing Curtius rearrangements as a continuous flow process

Marcus Baumann, Ian R. Baxendale, Steven V. Ley, Nikzad Nikbin, Christopher D. Smith, Jason Tierney

Organic & Biomolecular Chemistry · 2008 · 127 citations · 43 references

DOIFull text

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Concepts

Abstract

The use of a mesofluidic flow reactor is described for performing Curtius rearrangement reactions of carboxylic acids in the presence of diphenylphosphoryl azide and trapping of the intermediate isocyanates with various nucleophiles.

References

43

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