Robert N. Bream

Multi-step organic synthesis using solid-supported reagents and scavengers: a new paradigm in chemical library generation

Steven V. Ley, Ian R. Baxendale, Robert N. Bream et al. · Journal of the Chemical Society Perkin Transactions 1 · 2000 · 688 citations · Full text

Combinatorial Chemistry, Literary Theory, Engineering +20

Asymmetric Allylic Alkylation of Cyclic Vinylogous Esters and Thioesters by Pd‐Catalyzed Decarboxylation of Enol Carbonate and β‐Ketoester Substrates

Barry M. Trost, Robert N. Bream, Jiayi Xu · Angewandte Chemie International Edition · 2006 · 170 citations

γ-Disubstituted Cycloalkenones, Cross-coupling Reaction, Convenient Protocol +13

Asymmetric Allylic Alkylation of Cyclic Vinylogous Esters and Thioesters by Pd‐Catalyzed Decarboxylation of Enol Carbonate and β‐Ketoester Substrates

Barry M. Trost, Robert N. Bream, Jiayi Xu · Angewandte Chemie · 2006 · 139 citations

Synthesen Wichtig Sind, Engineering, Enol Carbonate +12

Design and Application of a DNA-Encoded Macrocyclic Peptide Library

Zhengrong Zhu, Alex Shaginian, LaShadric C. Grady et al. · ACS Chemical Biology · 2017 · 103 citations

Formation of <i>N</i>-Nitrosamine Drug Substance Related Impurities in Medicines: A Regulatory Perspective on Risk Factors and Mitigation Strategies

Răzvan C. Cioc, Ciarán Joyce, Monika Mayr et al. · Organic Process Research & Development · 2023 · 87 citations · Full text

Pharmaceutical Science, Bioorganic Chemistry, Pharmacotherapy +24