Microwave assisted organic synthesis—a review

Pelle Lidström, Jason Tierney, Bernard Wathey, +1

Tetrahedron

EngineeringSustainable SynthesisOrganic ChemistryOrganic Synthesis—a ReviewChemistry +3

A modular flow reactor for performing Curtius rearrangements as a continuous flow process

Marcus Baumann, Ian R. Baxendale, Steven V. Ley, +3

Organic & Biomolecular Chemistry

Process IntensificationFlow ChemistryEngineeringModular Flow ReactorChemical Transformation +13

Catalytic enantioselective deprotonation of meso-epoxides utilising homochiral bis-lithium amide bases

Jason Tierney, Alexandre Alexakis, Pierre Mangeney

Tetrahedron Asymmetry

Chemical EngineeringEngineeringCatalytic Enantioselective DeprotonationOrganometallic CatalysisCatalysis +4

Solid Phase Organic Synthesis

Catherine McCusker, Fiona McKerlie, Tanya Wildman, +2

Journal of the Chemical Society Perkin Transactions 1

Combinatorial ChemistryExperimental SynthesisPerkin 1EngineeringNew Linker Design +6

Solid-Supported Cyclohexane-1,3-dione (CHD):  A “Capture and Release” Reagent for the Synthesis of Amides and Novel Scavenger Resin

Cara E. Humphrey, Morag A. M. Easson, Jason Tierney, +1

Organic Letters

Organic Material ChemistryChemical EngineeringNovel OrganocatalystsEngineeringResin 6 +11

Design, synthesis, and structure–activity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB1 receptor agonists

Julia M. Adam, Jim Cairns, Wilson Caulfield, +18

MedChemComm

Pharmaceutical ScienceDrug TargetPain MedicineLead IdentificationPharmacotherapy +15

Discovery of a Novel Class of <scp>d</scp> -Amino Acid Oxidase Inhibitors Using the Schrödinger Computational Platform

Haifeng Tang, Kristian H. R. Jensen, Evelyne M. Houang, +32

Journal of Medicinal Chemistry

Design, synthesis, and structure–activity relationship study of bicyclic piperazine analogs of indole-3-carboxamides as novel cannabinoid CB1 receptor agonists

Elizabeth M. Moir, Kazuya Yoshiizumi, Jim Cairns, +14

Bioorganic & Medicinal Chemistry Letters

Cannabis UseFunctional SelectivityStructure–activity Relationship StudyBicyclic Piperazine AnalogsMedicine +5

Template-directed intramolecular C-glycosidation. cation-mediated synthesis of ketooxetanes from thioglycosides

Donald C. Craig, V. Ranjit N. Munasinghe, Jason Tierney, +3

Tetrahedron

BiochemistryGlycobiologyTemplate-directed Intramolecular C-glycosidationNatural Product SynthesisCarbohydrate-protein Interaction +1

Identification of a Potent, Selective, and Brain-Penetrant Rho Kinase Inhibitor and its Activity in a Mouse Model of Huntington’s Disease

Tammy Ladduwahetty, Matthew R. Lee, Michel Maillard, +22

Journal of Medicinal Chemistry

Drug TargetNeurochemical BiomarkersMedicinal ChemistryScaffold HoppingRho Kinase +17