Concepedia

Functional Variants of the Central Bile Acid Sensor FXR Identified in Intrahepatic Cholestasis of Pregnancy

Saskia W. C. van Mil, Alexandra Milona, Peter Dixon, Roman Müllenbach, Victoria Geenes, Jenny Chambers, Vasylyna Shevchuk, Gudrun E. Moore, Frank Lammert, Anna Glantz,

Gastroenterology · 2007 · 258 citations · 44 references

DOI

Concepts

References

44

Identification of a Nuclear Receptor for Bile Acids

Makoto Makishima, Arthur Y. Okamoto, Joyce J. Repa et al. · Science · 1999 · 2.7K citations

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Bile Acids: Natural Ligands for an Orphan Nuclear Receptor

Derek J. Parks, Steven G. Blanchard, Randy K. Bledsoe et al. · Science · 1999 · 2.2K citations

, , +17

A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis

Bryan Goodwin, Stacey A. Jones, Roger R. Price et al. · Molecular Cell · 2000 · 1.9K citations · Full text

, , +16

Estrogen Receptor-α Directs Ordered, Cyclical, and Combinatorial Recruitment of Cofactors on a Natural Target Promoter

Raphaël Métivier, Graziella Penot, Michael R. Hübner et al. · Cell · 2003 · 1.4K citations · Full text

, , +16

Intrahepatic cholestasis of pregnancy: Relationships between bile acid levels and fetal complication rates

Anna Glantz, Hanns–Ulrich Marschall, L. Mattsson · Hepatology · 2004 · 841 citations · Full text

, , +15