Uronic Acids in Oligosaccharide Synthesis

Leendert J. van den Bos, Jeroen D. C. Codée, Remy E. J. N. Litjens, Jasper Dinkelaar, Herman S. Overkleeft, Gijsbert A. van der Marel

European Journal of Organic Chemistry · 2007 · 90 citations · 136 references

Concepts

Abstract

Abstract This Microreview covers some general strategies for the preparation of uronic acid residues and their incorporation into anionically charged oligosaccharides. Two distinct strategies can be recognized: (1) glycosylation followed by oxidation, and (2) oxidation of the monosaccharide building blocks followed by glycosylation. Examples of both strategies are discussed, with a focus on the advantages and disadvantages of the respective strategies. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)

References

136