Identification of expressed genes by laser-mediated manipulation of single cells

Genetic Alterations during Colorectal-Tumor Development

Bert Vogelstein, Eric R. Fearon, Stanley R. Hamilton et al. · New England Journal of Medicine · 1988 · 6.7K citations

Tumor Biology, Somatic Variant, Tumor Heterogeneity +13

Detection of high incidence of K-ras oncogenes during human colon tumorigenesis

Kathleen Forrester, Concepción Almoguera, Kyuhyung Han et al. · Nature · 1987 · 1.1K citations

Tumor Biology, Oncology, Oncogenic Agent +11

Laser Capture Microdissection: Molecular Analysis of Tissue

Robert F. Bonner, Michael R. Emmert‐Buck, Kristina A. Cole et al. · Science · 1997 · 881 citations

Engineering, Genetics, Laser Capture Microdissection +17

Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development.

Ralf Küppers, Klaus Rajewsky, Min Zhao et al. · Proceedings of the National Academy of Sciences · 1994 · 685 citations · Full text

Lymphocyte Development, Immunodeficiencies, Immunology +21

Ablation of Polymers and Biological Tissue by Ultraviolet Lasers

R. Srinivasan · Science · 1986 · 560 citations

Ultraviolet Lasers, Laser Radiation, Engineering +17