Interaction of human PD-L1 and B7-1

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

Gordon J. Freeman, Andrew J. Long, Yoshiko Iwai et al. · The Journal of Experimental Medicine · 2000 · 5.2K citations · Full text

Restoring function in exhausted CD8 T cells during chronic viral infection

Daniel L. Barber, E. John Wherry, David Masopust et al. · Nature · 2005 · 3.9K citations

T-regulatory Cell, Immunology, Virology +8

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

Cheryl L. Day, Daniel E. Kaufmann, Photini Kiepiela et al. · Nature · 2006 · 2.6K citations

T-cell Exhaustion, Autoimmune Disease, Pd-1 Expression +10

Programmed Death-1 Ligand 1 Interacts Specifically with the B7-1 Costimulatory Molecule to Inhibit T Cell Responses

Manish J. Butte, Mary Keir, Theresa B. Phamduy et al. · Immunity · 2007 · 1.7K citations · Full text

Cancer Immunosurveillance, T-regulatory Cell, Apoptosis +11

Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

Lydie Trautmann, Loury Janbazian, Nicolas Chomont et al. · Nature Medicine · 2006 · 1.5K citations

Autoimmune Disease, Pd-1 Expression, Human Retrovirus +10