Characterisation of the PTEN inhibitor VO-OHpic

<i>PTEN</i> , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

Jing Li, Clifford Yen, Danny Liaw et al. · Science · 1997 · 4.8K citations

Medicine, Molecular Genetics, Oncology +16

The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate

Tomohiko Maehama, Jack E. Dixon · Journal of Biological Chemistry · 1998 · 3.1K citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

Peter A. Steck, Mark A. Pershouse, Samar A. Jasser et al. · Nature Genetics · 1997 · 2.8K citations

Life Sciences, Genetics, Molecular Genetics +11

Crystal Structure of the PTEN Tumor Suppressor

Jie‐Oh Lee, Haijuan Yang, Maria-Magdalena Georgescu et al. · Cell · 1999 · 1K citations · Full text

Life Sciences, Molecular Biology, Oncology +14

Tenets of PTEN Tumor Suppression

Leonardo Salmena, Arkaitz Carracedo, Pier Paolo Pandolfi · Cell · 2008 · 1K citations · Full text

Medicine, Cancer Biology, Oncology +12